# Postmenopausal Presentation of Granulosa Cell Tumor: A Case Report

**Authors:** Risha Patel, Anuja Bhalerao, Ojas Bondre

PMC · DOI: 10.7759/cureus.77175 · Cureus · 2025-01-09

## TL;DR

A postmenopausal woman with a granulosa cell tumor in her left ovary underwent surgery and was diagnosed at stage IIIA2, highlighting the need for long-term follow-up and multidisciplinary care.

## Contribution

This case report emphasizes the importance of multidisciplinary coordination in diagnosing and treating rare ovarian tumors in postmenopausal women.

## Key findings

- The patient presented with a pelvic-abdominal mass confirmed as stage IIIA2 granulosa cell tumor via histopathology.
- Surgical intervention included hysterectomy, bilateral salpingo-oophorectomy, and lymphadenectomy.
- The case underscores the necessity of long-term follow-up due to the risk of late recurrence in granulosa cell tumors.

## Abstract

The granulosa cells found in the ovarian follicles give rise to malignant neoplasms known as granulosa cell tumors (GCTs). The majority of the diagnoses are reported in Stage I and surgery is the main intervention for the adult form, which is frequently reported. Hence, the current report presents a case of GCT in postmenopausal women who reported the chief complaints of pain in the abdomen on the left side, bloating since three to four days, and the presence of spotting in the previous month. On general examination, a mass of 18 weeks was palpated which was firm, tender, and mobile. Moreover, Magnetic Resonance Imaging (MRI) showed the presence of a solid cystic pelvic-abdominal lesion that was suggestive of malignant epithelial neoplastic etiology of ovarian origin. Based on the findings, staging laparotomy was planned and commenced along with abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and peritoneal biopsy with iliac lymphadenectomy. The histopathology (HPE) report revealed the presence of GCT in the left ovary (stage IIIA2). Hence, despite the generally favorable prognosis for early-stage GCTs, vigilance in long-term follow-up is crucial due to the potential for late recurrence. To execute appropriate and timely intervention and customized treatment regimens, this case highlights the significance of multidisciplinary coordination in the diagnosis and treatment of ovarian tumors that are uncommon.

## Linked entities

- **Diseases:** granulosa cell tumor (MONDO:0006036), ovarian tumor (MONDO:0021068)

## Full-text entities

- **Diseases:** pelvic-abdominal lesion (MESH:D000008), GCTs (MESH:D006106), malignant neoplasms (MESH:D009369), GCT (MESH:C537296), pain in the abdomen (MESH:D000006), ovarian tumors (MESH:D010051)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11806361/full.md

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Source: https://tomesphere.com/paper/PMC11806361