Author's Reply to “Digital Devices for Arrhythmia Detection: What Is Still Missing?”
Martin Manninger, David Zweiker, Tatevik Hovakimyan, Paweł T. Matusik, Sergio Conti, Pierre Ollitrault, Aapo Aro, Bart A. Mulder, Wolfgang Dichtl, Christian‐Hendrik Heeger, Rachel M. A. ter Bekke, Enes Elvin Gul, Bob Weijs, Ann‐Kathrin Rahm, Angeliki Darma, Banu Evranos

Abstract
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Taxonomy
TopicsAtrial Fibrillation Management and Outcomes · Cardiac Arrhythmias and Treatments · ECG Monitoring and Analysis
We thank Kataoka and Imamura for their interest in our recently published survey on physician's preferences in the use of novel digital devices in the management of patients with atrial fibrillation (AF) [1, 2].
Our survey shows, that digital devices are beginning to be implemented in clinical practice. We respectfully disagree with Kataoka and Imamura that the debate on the type of monitoring technology is not critical at the moment. Our international group of authors strongly believe that the switch to increased patient involvement, to patient‐initiated rhythm monitoring and to telemedical care require physician (and not industry) driven education on the technologies used, recommendations for specific diagnostic pathways, cost‐effectiveness analyses and outcome‐centered research [3, 4, 5, 6, 7, 8].
The clinical scenarios presented in this survey do not aim to give specific recommendations on diagnostic pathways but aim to reflect common clinical scenarios we experience as physicians in daily clinical practice. Diagnostic pathways for these scenarios are reflected in current clinical practice guidelines: There is a clear recommendation to confirm AF in symptomatic patients and to screen for AF in patients at risk [5, 6]. We agree with the Kataoka and Imamura that the duration of monitoring is crucial and still one of the unanswered questions, but first, there is evolving data in this field and second, screening duration using novel digital devices is often self‐determined by patients [9, 10].
We agree with Kataoka and Imamura's opinion that AF screening in the general population shows questionable benefit. As the Apple Heart Study showed, even the number needed to screen to diagnose AF is exceptionally high [11]. Consequently, the number needed to screen to show clinical benefit in this population are expected to be even higher. However, the presented patient scenarios reflect opportunistic testing for AF in patients with risk factors for adverse outcomes as a result of under‐detected AF, which represents a clinical challenge in several outpatient clinics [6].
We believe that novel digital devices for rhythm monitoring provide important diagnostic tools for screening, diagnosis and management of AF when used in the right populations at risk/patients. These devices may increase patient's adherence to treatment and even decrease anxiety related to known recurrences of benign arrhythmias. Referring to the author's question: “Digital Devices for Arrhythmia Detection: What is Still Missing?”: More physician and patient education on the potential of novel digital devices is required to achieve diagnostic pathways as suggested by the EHRA practical guide [5].
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1M. Manninger , D. Zweiker , T. Hovakimyan , et al., “Physician Preferences in Using Novel Digital Devices for the Management of Atrial Fibrillation‐A DAS‐CAM III Survey,” Clinical Cardiology 47 (2024): e 24331.39582318 10.1002/clc.24331 PMC 11586575 · doi ↗ · pubmed ↗
- 2N. Kataoka and T. Imamura , “Digital Devices for Arrhythmia Detection: What Is Still Missing?,” Clinical Cardiology 48 (2025): e 70074.39713932 10.1002/clc.70074 PMC 11664457 · doi ↗ · pubmed ↗
- 3M. Gawałko , D. Duncker , M. Manninger , et al., “The European Telecheck‐AF Project on Remote App‐Based Management of Atrial Fibrillation During the COVID‐19 Pandemic: Centre and Patient Experiences,” EP Europace 23 (2021): 1003–1015.33822029 10.1093/europace/euab 050PMC 8083545 · doi ↗ · pubmed ↗
- 4A. N. L. Hermans , R. M. J. van der Velden, , M. Gawalko , et al., “On‐Demand Mobile Health Infrastructures to Allow Comprehensive Remote Atrial Fibrillation and Risk Factor Management Through Teleconsultation,” Clinical Cardiology 43 (2020): 1232–1239.33030259 10.1002/clc.23469 PMC 7661648 · doi ↗ · pubmed ↗
- 5E. Svennberg , F. Tjong , A. Goette , et al., “How to Use Digital Devices to Detect and Manage Arrhythmias: An EHRS Practical Guide,” Europace 24 (2022): 979–1005.35368065 10.1093/europace/euac 038PMC 11636571 · doi ↗ · pubmed ↗
- 6I. C. Van Gelder , M. Rienstra , K. V. Bunting , et al., “2024 ESC Guidelines for the Management of Atrial Fibrillation Developed in Collaboration With the European Association for Cardio‐Thoracic Surgery (EACTS),” European Heart Journal 45 (2024): 3314–3414.39210723 10.1093/eurheartj/ehae 176 · doi ↗ · pubmed ↗
- 7M. Manninger , J. Kosiuk , D. Zweiker , et al., “Role of Wearable Rhythm Recordings in Clinical Decision Making—The Wehrables Project,” Clinical Cardiology 43 (2020): 1032–1039.32700414 10.1002/clc.23404 PMC 7462183 · doi ↗ · pubmed ↗
- 8M. Manninger , D. Zweiker , E. Svennberg , et al., “Current Perspectives on Wearable Rhythm Recordings for Clinical Decision‐Making: the w EHR Ables 2 Survey,” Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology 23 (2021), https://pubmed-1ncbi-1nlm-1nih-1gov-10013 b 5rr 0074.han.medunigraz.at/33842972/.10.1093/europace/euab 06433842972 · doi ↗ · pubmed ↗
