# Endoscopic Ultrasound-Guided Hepaticogastrostomy for a Benign Biliary Stricture in a Patient Allergic to Both Iodinated and Gadolinium Contrast Media: A Case Report

**Authors:** Koji Takahashi, Hiroshi Ohyama, Izumi Ohno, Naoya Kato

PMC · DOI: 10.7759/cureus.77072 · Cureus · 2025-01-07

## TL;DR

A new method for biliary drainage was used in a patient allergic to common contrast agents, avoiding complications and improving liver function.

## Contribution

EUS-HGS is presented as a safe alternative for biliary drainage in patients with allergies to iodinated and gadolinium contrast media.

## Key findings

- EUS-HGS was successfully performed without contrast agents in a patient with dual allergies.
- The patient's hepatobiliary enzyme levels improved significantly after the procedure.
- The procedure was complication-free and effective for biliary drainage.

## Abstract

Allergic reactions to iodinated and gadolinium contrast media, though rare, present significant challenges in managing biliary obstructions. This case report describes a novel approach to biliary drainage in a patient with such allergies using endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS). An 81-year-old woman with multiple allergies, including to both iodinated and gadolinium contrast media, developed a benign biliary stricture following repeated radiofrequency ablation for hepatocellular carcinoma. Standard endoscopic retrograde cholangiopancreatography was contraindicated due to these allergies. An EUS-HGS was successfully performed, achieving effective biliary drainage through ultrasound-guided puncture and stent placement without the use of contrast agents. The procedure was complication-free, and the patient’s hepatobiliary enzyme levels improved significantly postoperatively. An EUS-HGS offers a safe and effective alternative for biliary drainage in patients with dual contrast agent allergies, especially when conventional methods are not viable. This case highlights the potential of EUS-HGS in addressing complex clinical challenges.

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Diseases:** biliary obstructions (MESH:D001658), Biliary Stricture (MESH:D003251), allergies (MESH:D004342), hepatocellular carcinoma (MESH:D006528)
- **Chemicals:** Iodinated (-), Gadolinium (MESH:D005682)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11800723/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11800723/full.md

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Source: https://tomesphere.com/paper/PMC11800723