# Didelphys uterus: a successful induction of labor in a case of intrauterine fetal death near term

**Authors:** Algeri Paola, D’Oria Patrizia, Toto Valentina, Fenili Paola, Ermito Santina, Bonalumi Silvia, Rinaldo Denise, Ciammella Massimo

PMC · DOI: 10.1515/crpm-2021-0078 · Case Reports in Perinatal Medicine · 2022-02-23

## TL;DR

A woman with a didelphys uterus and diabetes successfully induced labor after fetal death near term using Mifepristone and Dinoprostone.

## Contribution

Demonstrates the safe use of Mifepristone and Dinoprostone for labor induction in a didelphys uterus with fetal demise.

## Key findings

- Mifepristone and Dinoprostone combination successfully induced labor in a didelphys uterus.
- Vaginal delivery was uneventful despite Müllerian anomaly and diabetes.
- Pre-gestational evaluation is recommended for women with chronic diseases.

## Abstract

Müllerian anomalies are associated with infertility and worse pregnancy outcomes.

A 34-years-old primigravida patient affected by didelphys uterus and type 2 diabetes mellitus was admitted at 36.4 weeks with intrauterine fetal death. Labor was induced with oral Mifepristone and vaginal Dinoprostone. She had an uneventful vaginal delivery.

Pre-gestational evaluation should be recommended in each woman, in order to optimize clinical conditions in case of a chronic disease; moreover, if the patient is infertile Müllerian malformations should be excluded. In a didelphys uterus, the combination of Mifepristone and Dinoprostone could be a safe option for labor induction.

## Linked entities

- **Chemicals:** Mifepristone (PubChem CID 4196), Dinoprostone (PubChem CID 5280360)
- **Diseases:** intrauterine fetal death (MONDO:0041526), type 2 diabetes mellitus (MONDO:0005148)

## Full-text entities

- **Diseases:** Mullerian anomalies (MESH:C537371), Didelphys uterus (MESH:D000093642), intrauterine fetal death (MESH:D005313), type 2 diabetes mellitus (MESH:D003924), infertility (MESH:D007246)
- **Chemicals:** Dinoprostone (MESH:D015232), Mifepristone (MESH:D015735)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11800674/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11800674/full.md

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Source: https://tomesphere.com/paper/PMC11800674