# Clinical forms of 5 cases of circumcised penile cancer in immunocompetent subjects in Abidjan (Ivory Coast)

**Authors:** Evrard Kouame Yao, Abraham Hognou Yao, Donafologo Daouda Yeo, Tawakaltu Adebayo, Michel Tuo, Freddy Junior Zouan, Noel Coulibaly

PMC · DOI: 10.1186/s12610-025-00253-6 · Basic and Clinical Andrology · 2025-02-06

## TL;DR

This paper describes five rare cases of penile cancer in circumcised, immunocompetent men in Abidjan, highlighting the varied clinical presentation and the importance of biopsy for diagnosis.

## Contribution

The novelty lies in documenting penile cancer cases in circumcised men, a group typically considered at lower risk, emphasizing the need for vigilance in diagnosis.

## Key findings

- Five penile cancer cases were identified in circumcised, immunocompetent men aged 44 to 70.
- Three cases were squamous cell carcinoma, one was fusosarcoma, and one was metastatic squamous cell carcinoma.
- All patients refused surgical treatment despite the polymorphous and misleading clinical features of the disease.

## Abstract

Malignant tumours of the penis are rare. Their incidence varies around the world and increases with age. Treatment is essentially surgical. Surgery may be conservative or radical.

We report the anatomoclinical aspects of 5 cases of penile cancer observed in our department.

A 44-year-old patient with a circumcised penis, diagnosed with a fusosarcoma (a rare type of sarcoma) of the penis. Three patients (ages 61, 59, and 70) were diagnosed with squamous cell carcinoma, the most common type of penile cancer. These patients also had circumcised penises. The last case was a metastatic squamous cell carcinoma of the penis in a 68-year-old patient. All patients were immunocompetent and had a circumcised penis. They refused surgery in any form.

The clinical aspects of penile cancer are polymorphous and misleading. Any bulging or indurated lesions on the penis should be biopsied.

## Linked entities

- **Diseases:** penile cancer (MONDO:0001325), squamous cell carcinoma (MONDO:0005096)

## Full-text entities

- **Diseases:** squamous cell carcinoma (MESH:D002294), Malignant tumours of the penis (MESH:D010412), sarcoma (MESH:D012509)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

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Source: https://tomesphere.com/paper/PMC11800465