# Unmasking the Intruder: A Case of Lung Carcinoma Mimicking As Glioma

**Authors:** Joana Christopher, Thanka Johnson, Anbukkarasi Kannan, Santhanam Rengarajan

PMC · DOI: 10.7759/cureus.68035 · Cureus · 2024-08-28

## TL;DR

A lung cancer case was mistaken for a brain tumor, highlighting the need for accurate diagnosis and collaboration in complex medical cases.

## Contribution

This case emphasizes the importance of histopathology in distinguishing brain metastases from primary brain tumors.

## Key findings

- A 73-year-old male initially diagnosed with a high-grade glioma was found to have lung carcinoma with brain metastasis.
- The case underscores the diagnostic challenges of brain metastases mimicking primary brain tumors.
- Histopathological confirmation is crucial for accurate diagnosis and treatment planning.

## Abstract

Lung carcinoma with metastases to the brain typically involves the cerebral hemispheres, occasionally the cerebellum and rarely the brainstem. This report presents the case of a 73-year-old male who complained of neurological symptoms of left-sided limb weakness and was initially diagnosed with a high-grade glioma. With further radiological investigations, our patient was found to have primary bronchogenic carcinoma with metastasis to the brain. He underwent craniotomy with decompression of the mass and is currently undergoing chemotherapy. This case calls for the collaborative effort needed to diagnose brain metastases and the importance of histopathology for confirmation of the same.

## Linked entities

- **Diseases:** Lung carcinoma (MONDO:0005138), high-grade glioma (MONDO:0100342), bronchogenic carcinoma (MONDO:0002806)

## Full-text entities

- **Diseases:** metastases (MESH:D009362), bronchogenic carcinoma (MESH:D002283), Glioma (MESH:D005910), metastases to the brain (MESH:D001932), Lung Carcinoma (MESH:D008175), neurological symptoms (MESH:D009461), left-sided limb weakness (MESH:C537001)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11432779/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11432779/full.md

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Source: https://tomesphere.com/paper/PMC11432779