# Iliopsoas Abscess, Spondylodiscitis, Septic Pulmonary Embolism, and Symmetrical Peripheral Gangrene by Hypermucoviscous Klebsiella pneumoniae

**Authors:** Hina Hamada, Koji Hayashi, Yukie Morikawa, Maho Hayashi, Akihisa Shirasaki, Chie Yamamoto

PMC · DOI: 10.7759/cureus.67985 · 2024-08-28

## TL;DR

A rare and severe infection caused by hypermucoviscous Klebsiella pneumoniae was successfully treated with long-term antibiotics and supportive care.

## Contribution

This case report highlights the successful treatment of a complex hmKP infection involving multiple severe complications.

## Key findings

- The patient was infected with hypermucoviscous Klebsiella pneumoniae causing iliopsoas abscess, spondylodiscitis, septic pulmonary embolism, and SPG.
- A 148-day antibiotic therapy with rifampicin and supportive care led to a good clinical outcome.
- Non-invasive ventilation and hemodialysis were part of the successful treatment strategy.

## Abstract

Hypermucoviscous Klebsiella pneumoniae (hmKP) is a bacterium known to cause lesions, including abscesses, in various organs. Unlike typical Klebsiella pneumoniae, hmKP can yield a positive string test in culture specimens. Infections caused by hmKP often become severe and are associated with a poor prognosis. In this report, we describe a case of iliopsoas abscess, spondylodiscitis, septic pulmonary embolism, and symmetrical peripheral gangrene (SPG) caused by hmKP. The patient received non-invasive positive-pressure ventilation, hemodialysis, platelet transfusions, fresh frozen plasma, thrombomodulin, and intensive antibiotic therapy including rifampicin. The patient underwent 148 days of antibiotic therapy and achieved a good outcome.

## Linked entities

- **Chemicals:** rifampicin (PubChem CID 135398735)
- **Species:** Klebsiella pneumoniae (taxon 573)

## Full-text entities

- **Diseases:** Iliopsoas Abscess (MESH:D016659), abscesses (MESH:D000038), Peripheral Gangrene (MESH:D005734), Hypermucoviscous Klebsiella pneumoniae (MESH:D007710), Spondylodiscitis (MESH:D015299), Septic Pulmonary Embolism (MESH:D011655), Infections (MESH:D007239)
- **Chemicals:** rifampicin (MESH:D012293)
- **Species:** Homo sapiens (human, species) [taxon 9606], Klebsiella pneumoniae (species) [taxon 573]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11427936/full.md

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Source: https://tomesphere.com/paper/PMC11427936