# Treatment of Idiopathic Inflammatory Orbital Syndrome (IOIS) With Prominent Lacrimal Gland Involvement Using Oral Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

**Authors:** Hwee Minn Ling, Kit May Chow

PMC · DOI: 10.7759/cureus.67981 · 2024-08-27

## TL;DR

This paper reports a case where NSAIDs successfully treated a patient with idiopathic dacryoadenitis, a condition typically treated with corticosteroids.

## Contribution

The novelty lies in reporting a successful treatment of idiopathic dacryoadenitis using NSAIDs, which has not been formally studied before.

## Key findings

- NSAIDs were effective in treating idiopathic isolated dacryoadenitis in a reported case.
- This case suggests NSAIDs could be a viable alternative to corticosteroids for this condition.

## Abstract

Idiopathic orbital inflammatory syndrome (IOIS) is a chronic inflammatory process of unknown etiology, which can either be localized or diffuse. In cases where there is isolated inflammation of the lacrimal gland, it is known as dacryoadenitis. This study focuses on the treatment of a patient with IOIS with prominent lacrimal gland involvement. The mainstay of treatment for idiopathic isolated dacryoadenitis is oral corticosteroids, but non-steroidal anti-inflammatory drug (NSAIDs) is known to be effective in treating idiopathic dacryoadenitis as well. There is no formal study yet to evaluate the use of NSAIDs in treating idiopathic dacryoadenitis. Here, we report a case of idiopathic isolated dacryoadenitis which was successfully treated with NSAIDs.

## Linked entities

- **Diseases:** dacryoadenitis (MONDO:0004804)

## Full-text entities

- **Diseases:** dacryoadenitis (MESH:D003607), inflammation of the lacrimal gland (MESH:D007249), IOIS (MESH:D016727)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11427761/full.md

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Source: https://tomesphere.com/paper/PMC11427761