# Patricia Goldman-Rakic: A Pioneer in Cognitive Neuroscience

**Authors:** Deepti Avasthi

PMC · DOI: 10.7759/cureus.67915 · 2024-08-27

## TL;DR

This paper reviews the life and work of Patricia Goldman-Rakic, a pioneering neuroscientist who transformed our understanding of the prefrontal cortex and cognitive functions.

## Contribution

The paper highlights Goldman-Rakic's novel integration of anatomical, electrophysiological, and behavioral methods to study cognition.

## Key findings

- Goldman-Rakic's work established the prefrontal cortex's role in working memory and executive function.
- Her research provided foundational insights into the neural basis of higher cognitive functions.
- The paper emphasizes her lasting influence on cognitive neuroscience.

## Abstract

Patricia Goldman-Rakic (1937-2003) was a trailblazing neuroscientist whose groundbreaking work greatly advanced our understanding of the prefrontal cortex and its crucial role in higher cognitive functions like working memory and executive function. Her innovative research, which integrated anatomical, electrophysiological, and behavioral methods, provided foundational insights into the neural basis of cognition. This review underscores her significant contributions, personal challenges, and the enduring influence of her work in the field of neuroscience.

## Full-text entities

- **Diseases:** Psychiatric Disorders (MESH:D001523), attention deficit hyperactivity disorder (MESH:D001289), cognitive deficits (MESH:D003072), Schizophrenia (MESH:D012559)
- **Chemicals:** Dopamine (MESH:D004298)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC11426953