# Endoscopic submucosal dissection for hypopharyngeal cancer simultaneous with immunotherapy for renal cell carcinoma

## TL;DR

A patient with two cancers was successfully treated with a less invasive endoscopic procedure and immunotherapy, achieving full recovery.

## Contribution

Demonstrates the successful simultaneous treatment of hypopharyngeal cancer and renal cell carcinoma using endoscopic submucosal dissection and immunotherapy.

## Key findings

- The patient was cured of both superficial hypopharyngeal cancer and recurrent renal cell carcinoma.
- Endoscopic submucosal dissection proved less invasive and effective for hypopharyngeal cancer.
- Combining endoscopic treatment with immunotherapy yielded a good prognosis.

## Abstract

We report a case of a man who was diagnosed with superficial hypopharyngeal cancer and recurrence of renal cell carcinoma in the duodenum, liver, and gluteus medius muscle simultaneously. He underwent endoscopic submucosal dissection for hypopharyngeal cancer in parallel with systemic immunotherapy for recurrent renal cell carcinoma, resulting in completely overcoming both malignancies. Endoscopic submucosal dissection is less invasive and can be performed in a shorter duration for treating superficial hypopharyngeal cancer compared with other treatment options, such as radiation therapy, chemotherapy, and surgery. Additionally, endoscopic submucosal carcinoma is adequately effective in controlling local lesions and has a satisfactorily good prognosis.