# Osteomyelitis in the Nonunion of a Patellar Fracture

**Authors:** Athena Z Bennani, Brian Chegwidden, Liam Jones, Constantino G Lambroussis, Lorrie Penfield

PMC · DOI: 10.7759/cureus.67547 · Cureus · 2024-08-22

## TL;DR

A 64-year-old woman with a non-healing patellar fracture was diagnosed with rare patellar osteomyelitis and successfully treated with antibiotics, avoiding surgery.

## Contribution

This case highlights successful antibiotic treatment of patellar osteomyelitis without surgical debridement.

## Key findings

- MRI findings confirmed patellar osteomyelitis in a patient with nonunion of a patellar fracture.
- Antibiotic therapy (cefdinir and doxycycline) resolved the patient's pain and infection without the need for surgery.
- Early diagnosis and treatment improved recovery and reduced surgical risks.

## Abstract

Osteomyelitis is by definition any infection of the bone. It can have a hematogenous or non-hematogenous mechanism of infection, but comorbidities such as cardiovascular disease, diabetes mellitus, and the presence of orthopedic hardware can increase the risk of osteomyelitis. Our case focuses on a 64-year-old Caucasian female with multiple comorbidities who presented with a fractured right patella that was not healing four months after the occurrence of the fracture. The patient reported cramping, fasciculations, and severe pain that was worsening. She also reported that she received nine X-rays from different orthopedists before receiving an MRI, ordered by internal medicine. The MRI showed a small knee effusion with mild generalized edema of the nearby subcutaneous tissues and evidence of nonunion of the fracture as evidenced by fracture fragments of the right patella. The MRI additionally showed increased signal in the bone fragments of the right patella, as well as the anterior and posterior superior rims of the right tibial plateau, concerning for potential osteomyelitis. Referral to infectious disease confirmed the diagnosis of patellar osteomyelitis, a rather rare diagnosis. The patient was promptly started on cefdinir and doxycycline, and within days of starting antibiotic therapy, her right knee pain was reduced to zero. Surgical debridement was not necessary, and the patient was able to resume her daily activities with the pain resolved. The possibility of patients only having to undergo antibiotic treatment for patellar osteomyelitis improves their chances of a full recovery and reduces the risks associated with undergoing surgical debridement.

## Linked entities

- **Chemicals:** cefdinir (PubChem CID 6915944), doxycycline (PubChem CID 54671203)
- **Diseases:** osteomyelitis (MONDO:0005246), cardiovascular disease (MONDO:0004995), diabetes mellitus (MONDO:0005015)

## Full-text entities

- **Diseases:** fasciculations (MESH:D005207), knee effusion (MESH:D007718), Osteomyelitis (MESH:D010019), pain (MESH:D010146), infectious disease (MESH:D003141), infection (MESH:D007239), fracture (MESH:D050723), right patella (MESH:D000092462), Nonunion of (MESH:C538144), Patellar Fracture (MESH:D031222), cramping (MESH:D009120), infection of the bone (MESH:D001847), edema (MESH:D004487), cardiovascular disease (MESH:D002318), knee pain (MESH:D046788), diabetes mellitus (MESH:D003920)
- **Chemicals:** doxycycline (MESH:D004318), cefdinir (MESH:D000077525)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11416829/full.md

## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC11416829/full.md

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Source: https://tomesphere.com/paper/PMC11416829