# Dystrophia Adiposa Corneae: An Out-of-the-Box Diagnosis

**Authors:** Tushar Agrawal, Pranav More, Radhika Paranjpe, Vishakha Vatkar, Pradipta P Potdar

PMC · DOI: 10.7759/cureus.67580 · Cureus · 2024-08-23

## TL;DR

This paper reports a rare corneal condition called dystrophia adiposa corneae in a 40-year-old Indian man, emphasizing the importance of recognizing this vision-threatening disorder.

## Contribution

The paper presents a rare clinical case of dystrophia adiposa corneae with detailed diagnostic findings and highlights its distinct features.

## Key findings

- Bilateral peripheral lipid deposition in the corneal stroma was observed, progressing to an annular shape.
- Cholesterol crystals and crystalline structures were identified without neovascularization.
- The patient had mild dyslipidaemia, linking systemic lipid issues to the corneal pathology.

## Abstract

Dystrophia adiposa corneae is a degenerative corneal disorder characterised by fatty deposition, leading to corneal opacity and reduced visual acuity. We report a case of an Indian male in his early 40s with bilateral peripheral deep lipid deposition in the corneal stroma, beginning in an arcuate fashion and progressing to an annular-shaped structure. Furthermore, cholesterol crystals, as well as crystalline structures, were seen without any neovascularisation. We confirmed these findings on anterior segment optical coherence tomography (AS-OCT). We also noticed an increase in central corneal thickness (CCT), and on systemic workup, the patient was diagnosed with mild dyslipidaemia. This case highlights the need for an out-of-the-box diagnosis of a rare keratopathy, which can be vision-threatening and needs to be differentiated from its mimickers.

## Linked entities

- **Chemicals:** cholesterol (PubChem CID 5997)
- **Diseases:** dyslipidaemia (MONDO:0002525)

## Full-text entities

- **Diseases:** Dystrophia Adiposa Corneae (MESH:C535478), visual acuity (MESH:D014786), keratopathy (MESH:C562399), corneal opacity (MESH:D003318), corneal disorder (MESH:D003316)
- **Chemicals:** lipid (MESH:D008055), cholesterol (MESH:D002784)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11416827/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11416827/full.md

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Source: https://tomesphere.com/paper/PMC11416827