# Extra-Acral Minute Synovial Sarcoma: A Case Report With Literature Review

**Authors:** John Grove, Rana Naous

PMC · DOI: 10.7759/cureus.67505 · Cureus · 2024-08-22

## TL;DR

This paper reports the first case of a rare synovial sarcoma smaller than one centimeter occurring in the abdomen, not the typical hand or foot locations.

## Contribution

The study presents the first documented case of a minute synovial sarcoma at an extra-acral site.

## Key findings

- A 0.6 cm synovial sarcoma was found in the abdomen of a 30-year-old female.
- The diagnosis was confirmed through histomorphology, immunohistochemistry, and molecular testing.
- This case expands the known locations for minute synovial sarcomas beyond acral regions.

## Abstract

Synovial sarcoma is a malignant soft tissue tumor of uncertain differentiation. It is typically seen in the deep soft tissue of the extremities; however, it has been reported to occur anywhere in the body. Synovial sarcoma by histomorphology has multiple subtypes, including monophasic spindle cell, biphasic and poorly differentiated subtypes. Synovial sarcomas measuring less than one centimeter in diameter are termed “minute” synovial sarcomas. “Minute” synovial sarcomas have only been reported so far in the acral region of the hands and feet. They are extremely rare and can often be misinterpreted as benign neoplasms. Herein, we report the findings in a 30-year-old female presenting with a palpable mass within the deep subcutaneous tissue along the anterior aspect of her right rectus abdominis muscle. The mass was excised and measured 0.6 cm in greatest dimension with histomorphology findings, immunohistochemical and molecular workup confirming the diagnosis of “minute” synovial sarcoma. Our findings represent the first documented case of a “minute” synovial sarcoma occurring at an extra-acral site. With such unique finding not yet reported in the literature, this case highlights the importance of considering synovial sarcoma in the differential diagnosis of subcutaneous abdominal masses.

## Linked entities

- **Diseases:** synovial sarcoma (MONDO:0010434)

## Full-text entities

- **Diseases:** soft tissue tumor (MESH:D012983), benign neoplasms (MESH:D009369), subcutaneous abdominal masses (MESH:D000007), Synovial Sarcoma (MESH:D013584)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11416138/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11416138/full.md

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Source: https://tomesphere.com/paper/PMC11416138