# Differentiating Myelography Contrast from Intraventricular and Subarachnoid Hemorrhage Using Dual-Energy CT of the Head: A Case Report and a Review of Literature

**Authors:** James Garda, Sarah-Marie C Gonzalez, Harold Sonnier, Awais Z Vance

PMC · DOI: 10.7759/cureus.67416 · Cureus · 2024-08-21

## TL;DR

This paper shows how dual-energy CT can distinguish between iodine contrast and blood in the brain, improving diagnosis in emergency settings.

## Contribution

The paper demonstrates a practical application of DECT to resolve diagnostic ambiguity between blood and contrast in head imaging.

## Key findings

- DECT successfully ruled out hemorrhage by differentiating iodine contrast from blood in a clinical case.
- DECT provides material differentiation capabilities not available in standard SECT.
- The technique has potential to improve diagnostic accuracy in emergency neuroimaging.

## Abstract

Single-energy computed tomography (SECT) head is a common diagnostic tool to evaluate for intracranial hemorrhage in emergency settings due to its widespread accessibility and non-invasive nature. However, SECT has densitometric evaluation limitations. For example, hyperdensities on SECT such as blood product and iodine contrast appear similarly. Dual-energy CT (DECT) is a relatively under-utilized imaging modality that has the capability to differentiate between multiple materials. This imaging technique can be extremely useful in identifying materials that are otherwise indistinguishable from standard SECT.

The authors present a case of a patient with findings suspicious of intraventricular and subarachnoid hemorrhage on conventional SECT. The suspected hemorrhage was subsequently ruled out utilizing DECT, as iodinated contrast can be subtracted out, yielding an image that can differentiate iodine contrast from blood or other hyperdense material. The authors discuss the underlying physics, potential advantages, and limitations of the DECT.

## Linked entities

- **Chemicals:** iodine (PubChem CID 807)
- **Diseases:** subarachnoid hemorrhage (MONDO:0005099)

## Full-text entities

- **Diseases:** hemorrhage (MESH:D006470), intracranial hemorrhage (MESH:D020300), Intraventricular and Subarachnoid Hemorrhage (MESH:D013345)
- **Chemicals:** iodine (MESH:D007455)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11415003/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC11415003/full.md

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Source: https://tomesphere.com/paper/PMC11415003