# Cut-off values of coronary risk factors in women with hypothyroidism

**Authors:** Deepika Srivastava, Latheef S.A.A., Venkatramana P.

PMC · DOI: 10.6026/973206300200762 · Bioinformation · 2024-07-31

## TL;DR

This study finds that women with hypothyroidism have higher cardiovascular risk factors compared to healthy women, but the cut-off values for these factors are similar.

## Contribution

The study determines cut-off values for coronary risk factors in women with hypothyroidism and compares them to healthy controls.

## Key findings

- Women with hypothyroidism had higher BMI, waist circumference, triglycerides, and LDL-C than healthy women.
- All variables showed an AUC value of >0.6 in ROC analysis.
- Cut-off values for coronary risk factors in hypothyroid women are similar to those in healthy women.

## Abstract

Women with hypothyroidism are at higher risk of cardiovascular diseases and the consequent mortality. It is not known whether cut-off
values of coronary risk factors in women with hypothyroidism are the same as healthy women. This may help to initiate interventions as
early to prevent cardiovascular mortality. Therefore, this study was conducted to determine the cut-off values of coronary risk factors
in women with hypothyroidism. One hundred women patients with hypothyroidism were compared with 100 healthy controls. Significantly
higher mean body mass index (BMI), waist circumference (WC), triglycerides and low-density lipoprotein cholesterol (LDL-C) were observed
in women with hypothyroidism than without it. All variables showed an area under curve (AUC) value of >0.6 in receiver operator
characteristic curve (ROC) analysis, and similar to healthy women.

## Linked entities

- **Diseases:** hypothyroidism (MONDO:0005420)

## Full-text entities

- **Diseases:** hypothyroidism (MESH:D007037), cardiovascular diseases (MESH:D002318)
- **Chemicals:** triglycerides (MESH:D014280)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11414328/full.md

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Source: https://tomesphere.com/paper/PMC11414328