# A Rare Skin Lesion Presentation With Sarcoidosis

**Authors:** Sayed Hashem, Rafat Harby, Humoud Al-Sabah, Atlal Allafi

PMC · DOI: 10.7759/cureus.67269 · 2024-08-20

## TL;DR

This paper presents a rare case of sarcoidosis that first appeared as a skin lesion in a 31-year-old man.

## Contribution

The novelty lies in highlighting an unusual isolated cutaneous presentation of sarcoidosis.

## Key findings

- Skin biopsy confirmed non-caseating granulomas, characteristic of sarcoidosis.
- Treatment with intralesional triamcinolone acetonide was initiated.
- The case emphasizes the need for increased awareness of sarcoidosis's varied presentations.

## Abstract

Sarcoidosis is a multifaceted systemic disease of uncertain aetiology, pathologically characterised by non-caseating granulomas. Typical symptoms include coughing, dyspnoea, chest pain and lesions affecting the eyes or skin. Cutaneous sarcoidosis frequently accompanies the involvement of other organs, but isolated cutaneous presentations are also observed. We present a case of cutaneous sarcoidosis in a 31-year-old Indian male. The diagnosis of sarcoidosis was confirmed by a skin biopsy, which showed that there is a naked, non-caseating granuloma filling the upper and deep dermis, formed of epithelioid histiocytes and multinucleated giant cells. Treatment with the intralesional steroid triamcinolone acetonide (5 mg/mL) monthly is considered. We hope to raise doctors' awareness of the various forms of sarcoidosis, consequently improving diagnostic skills and patient treatment.

## Linked entities

- **Chemicals:** triamcinolone acetonide (PubChem CID 6436)
- **Diseases:** sarcoidosis (MONDO:0008399)

## Full-text entities

- **Diseases:** chest pain (MESH:D002637), Rare Skin Lesion (MESH:D035583), systemic disease (MESH:D034721), Cutaneous sarcoidosis (MESH:D012507), granuloma (MESH:D006099), coughing (MESH:D003371)
- **Chemicals:** steroid (MESH:D013256), triamcinolone acetonide (MESH:D014222)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11411394/full.md

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Source: https://tomesphere.com/paper/PMC11411394