Complex Neurological Sequelae: Axonal Guillain-Barré Syndrome Post COVID-19 in a Young Patient

TL;DR

A 46-year-old woman developed a rare and severe nerve disorder after a mild case of COVID-19, showing the need for specialized care and accurate diagnosis.

Contribution

This case highlights the diagnostic and therapeutic challenges of axonal Guillain-Barré Syndrome following mild COVID-19.

Findings

Axonal Guillain-Barré Syndrome can occur after mild COVID-19 infections.

The condition presents with severe muscle weakness and sensory deficits.

Multidisciplinary care is crucial for managing this rare neurological complication.

Abstract

Guillain-Barré syndrome (GBS) encompasses a spectrum of immune-mediated neuropathies, with axonal GBS representing a less common yet often severe subtype. This variant directly damages peripheral nerve axons, resulting in rapid and profound muscle weakness and sensory deficits. Axonal GBS has similar clinical features to the demyelinating form but is generally more severe with a less favorable prognosis. Here, we present a case of axonal GBS in a 46-year-old female following a mild COVID-19 infection, highlighting the diagnostic challenges and the importance of tailored therapeutic approaches and multidisciplinary care in managing this condition.

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