# Vein of Galen Aneurysmal Malformation Presenting As Persistent Pulmonary Hypertension in a Newborn: A Case Report

**Authors:** Barbara Amendolia, Vishwanath Bhat, Erica Poletto, Amar Jaspreet, Bradley Robinson

PMC · DOI: 10.7759/cureus.67191 · 2024-08-19

## TL;DR

A newborn with a rare brain blood vessel condition was misdiagnosed with lung-related high blood pressure before passing away from heart failure.

## Contribution

This case report highlights VOGM as a rare but critical cause of PPHN in infants.

## Key findings

- VOGM can present as PPHN in newborns, leading to delayed diagnosis.
- The patient died from high cardiac output heart failure due to untreated VOGM.
- Early recognition of VOGM is crucial for timely intervention in infants with PPHN.

## Abstract

We present a case of a newborn infant with a vein of Galen aneurysmal malformation (VOGM) who was admitted to our neonatal intensive care unit (NICU) with the diagnosis of persistent pulmonary hypertension of the newborn (PPHN). Further work-up at our institution, which included an echocardiogram and cranial ultrasound revealed VOGM. The patient was transferred to a children’s center for further management of the vascular malformation where the patient subsequently died from high cardiac output heart failure. This study highlights the importance of considering a VOGM as a rare cause of PPHN in an infant.

## Linked entities

- **Diseases:** persistent pulmonary hypertension of the newborn (MONDO:0022430)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** high cardiac output heart failure (MESH:D006333), vascular malformation (MESH:D054079), Pulmonary Hypertension (MESH:D006976), VOGM (MESH:C536535)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11409830/full.md

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Source: https://tomesphere.com/paper/PMC11409830