# Guillain–Barré syndrome in a 63-year-old patient possibly triggered by ehrlichiosis. Case report

## TL;DR

A 63-year-old man developed Guillain–Barré syndrome possibly triggered by Ehrlichia infection, with successful treatment using rifampicin after doxycycline failed.

## Contribution

First documented case in Honduran medical literature linking Ehrlichia infection to Guillain–Barré syndrome.

## Key findings

- Ehrlichia infection may act as a trigger for Guillain–Barré syndrome.
- Doxycycline was ineffective in treating the patient's Ehrlichia infection.
- Rifampicin successfully treated the Ehrlichia infection in the case report patient.

## Abstract

•Ehrlichia infection as a possible trigger for Guillain–Barré syndrome.•First-line treatment failure (doxycycline) in the case report patient.•Therapeutic success for Ehrlichia infection using rifampicin in case report patient.

Ehrlichia infection as a possible trigger for Guillain–Barré syndrome.

First-line treatment failure (doxycycline) in the case report patient.

Therapeutic success for Ehrlichia infection using rifampicin in case report patient.

Guillain–Barré syndrome is an immune-mediated acute demyelinating polyradiculoneuropathy, characterized by progressive flaccid weakness, triggered mainly by respiratory and gastrointestinal infections. We present the case of a 63-year-old male patient with a history of Ehrlichia infection, who consulted the internal medicine emergency department for lower back pain and progressive lower limb paresthesia, accompanied by decreased lower limb strength and nerve conduction velocity test, with results compatible with acute demyelinating sensorimotor polyradiculoneuropathy. To the best of our knowledge, this is the first documented case in Honduran medical literature; in our research, no other cases were found in Latin America or Europe. The importance of the topic and its dissemination in countries where Ehrlichia infection exists is that when cases of Guillain–Barré syndrome that cannot be associated with previous gastrointestinal or respiratory infection, they could be attributed to Ehrlichia infection as a possible cause; therefore, exhaustive preventive measures can be established regarding the transmitting vector of ehrlichiosis.