# Diagnostic utility of nasal methicillin-resistant Staphylococcus aureus polymerase chain reaction testing in head and neck infection

**Authors:** Jake Smith, Bailee Cummings, Ryan K. Dare

PMC · DOI: 10.1017/ash.2024.376 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2024-09-16

## TL;DR

This study shows that nasal MRSA PCR testing is highly accurate in predicting infection outcomes in head and neck surgery patients.

## Contribution

The study demonstrates 100% sensitivity and negative predictive value of nasal MRSA PCR compared to operative cultures.

## Key findings

- MRSA nasal PCR had 100% sensitivity in detecting infections.
- The negative predictive value of MRSA nasal PCR was 100%.
- The test could reliably rule out MRSA infection in surgical patients.

## Abstract

In this retrospective study of adult inpatients who underwent an ear, nose, and throat (ENT) surgery with operative cultures and collection of nasal methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reaction (PCR), we found that MRSA nasal PCR demonstrated 100% sensitivity and a negative predictive value (NPV) of 100% when compared to operative cultures.

## Linked entities

- **Species:** Staphylococcus aureus (taxon 1280)

## Full-text entities

- **Diseases:** head and neck infection (MESH:D006258)
- **Chemicals:** methicillin (MESH:D008712)
- **Species:** Homo sapiens (human, species) [taxon 9606], Staphylococcus aureus (species) [taxon 1280]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11406558/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11406558/full.md

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Source: https://tomesphere.com/paper/PMC11406558