# The Utility of Neuromuscular Assessment to Identify ADHD Among Patients with a Complex Symptom Picture

**Authors:** Anne Beate Helseth Udal, Liv Larsen Stray, Are Hugo Pripp, Torstein Stray, Jens Egeland

PMC · DOI: 10.1177/10870547241273102 · 2024-09-02

## TL;DR

This study explores how neuromuscular assessment can help identify ADHD in patients with complex psychiatric symptoms.

## Contribution

The study introduces neuromuscular dysregulation as a potential diagnostic marker for ADHD in psychiatric patients.

## Key findings

- Neuromuscular dysregulation was significantly linked to ADHD diagnosis but not to other disorders.
- MFNU scores showed varying sensitivity and specificity for ADHD diagnosis.
- The test may improve diagnostic accuracy for ADHD in patients with overlapping symptoms.

## Abstract

Diagnostic assessment of ADHD is challenging due to comorbid psychopathologies and symptoms overlapping with other psychiatric disorders. In this study, we investigate if a distinct pattern of neuromuscular dysregulation previously reported in ADHD, can help identifying ADHD in psychiatric patients with diverse and complex symptoms.

We explored the impact of neuromuscular dysregulation, as measured by The Motor Function Neurologic Assessment (MFNU), on the likelihood of being diagnosed with ADHD, affective disorder, anxiety disorder, or personality disorder among adults (n = 115) referred to a psychiatric outpatient clinic.

Logistic regression revealed that neuromuscular dysregulation was significantly associated with ADHD diagnosis only (OR 1.15, p < .01), and not with affective-, anxiety-, or personality disorders. Sensitivity and specificity for ADHD at different MFNU scores is provided.

A test of neuromuscular dysregulation may promote diagnostic accuracy in differentiating ADHD from other psychiatric disorders in patients with an overlapping symptom picture. This may have important implications for clinical practice. More studies are needed.

## Linked entities

- **Diseases:** ADHD (MONDO:0007743), anxiety disorder (MONDO:0005618), personality disorder (MONDO:0002028)

## Full-text entities

- **Diseases:** anxiety disorder (MESH:D001008), affective disorder (MESH:D019964), affective-, anxiety- (MESH:D001007), ADHD (MESH:D001289), neuromuscular dysregulation (MESH:D009468), personality disorder (MESH:D010554), psychiatric (MESH:D001523)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11403920/full.md

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Source: https://tomesphere.com/paper/PMC11403920