# Comparative analysis of the clinical effects of different thoracoscopic resection in the treatment of Stage I Non-Small Cell Lung Cancer

**Authors:** Hao Jiang, Tong Wu, Peng Qie, Huien Wang, Baoxin Zhang

PMC · DOI: 10.12669/pjms.40.8.9124 · Pakistan Journal of Medical Sciences · 2024-09-01

## TL;DR

This study compares thoracoscopic lobectomy and segmentectomy for early-stage lung cancer, finding that segmentectomy causes less bleeding, less pain, and fewer complications.

## Contribution

The study provides empirical evidence that thoracoscopic segmentectomy is more beneficial than lobectomy for stage I NSCLC patients.

## Key findings

- Segmentectomy resulted in less intraoperative blood loss and shorter hospital stays compared to lobectomy.
- Patients in the segmentectomy group experienced lower postoperative pain scores and fewer complications.
- Both procedures had similar lymph node dissection and pulmonary function outcomes preoperatively.

## Abstract

To compare and analyze the clinical effects of thoracoscopic lobectomy and segmentectomy in stage I non-small cell lung cancer (NSCLC).

This was a retrospective study. Eighty patients with stage I NSCLC treated in Cangzhou People’s Hospital from December 2019 to January 2022 were randomly divided into the segmentectomy group and lobectomy group, with 40 cases in each group. Further comparative analysis was carried out focusing on perioperative indexes, maximum ventilation volume (MVV), forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), VAS score of postoperative pain and complications.

There was no significant difference in the number of dissected lymph nodes and extubation time between the two groups (p>0.05). The operation time was longer, while intraoperative blood loss was less and the stay of stay in hospital was shorter in the segmentectomy group significantly than those in the lobectomy group (p<0.05). Furthermore, no significant difference was observed in MVV%, FVC% and FEV1% between the two groups before operation (p>0.05). Meanwhile, the segmentectomy group had evidently lower VAS scores at 1 d, 3 d and 5 d postoperatively than those in the lobectomy group (p<0.05). Besides, there was a much lower total incidence of complications in the segmentectomy group than that in the lobectomy group (p<0.05).

Compared with lobectomy, thoracoscopic segmentectomy is more effective in the treatment of stage I NSCLC, with less bleeding and mild pain, which can alleviate pulmonary function injury and reduce postoperative complications that is conducive to the improved prognosis of patients.

## Linked entities

- **Diseases:** Non-Small Cell Lung Cancer (MONDO:0005233)

## Full-text entities

- **Diseases:** NSCLC (MESH:D002289), pulmonary function injury (MESH:D055370), postoperative pain (MESH:D010149), complications (MESH:D008107), I (MESH:D006969), pain (MESH:D010146), bleeding (MESH:D006470)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11395368/full.md

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Source: https://tomesphere.com/paper/PMC11395368