# The Assessment of Auditory Function in High-Risk Neonates and Infants Using Brainstem-Evoked Response Audiometry (BERA)

**Authors:** Rashmi P Rajashekhar, Sunanda Devi Putta, Aishwarya Kothari, Mayur Ingale

PMC · DOI: 10.7759/cureus.66666 · Cureus · 2024-08-12

## TL;DR

This study shows that using BERA to screen high-risk infants for hearing loss helps detect issues early, which is crucial for their development.

## Contribution

The study provides empirical evidence on the prevalence of hearing loss in high-risk neonates using BERA.

## Key findings

- Prematurity was the most common risk factor for hearing loss in the studied infants.
- 50% of the infants had normal hearing, while 37% had mild or moderate hearing loss.
- Early detection through BERA allows for timely interventions like cochlear implants for severe cases.

## Abstract

Introduction

Hearing impairment in neonates and infants is a critical concern due to its potential to impede language acquisition, cognitive development, and overall quality of life. Brainstem-evoked response audiometry (BERA) stands out as a valuable diagnostic tool. The early detection of hearing impairments is paramount in neonatal care. Hearing loss during infancy can impede speech and language development, social interaction, and academic achievement. High-risk neonates, including those born prematurely or with low birth weight, have a heightened susceptibility to hearing impairment due to various factors such as exposure to ototoxic medications, mechanical ventilation, and complications associated with prematurity.

Methods

A hospital-based prospective study was conducted in the department of otorhinolaryngology; the study focused on high-risk neonates and infants from the outpatient department and inpatient department. The study was conducted from October 2022 to March 2024. A sample size of 70 patients was taken, including high-risk neonates and infants. Healthy term neonates and healthy infants were excluded from the study.

Results

In the current study, there were 40 males and 30 females. Among the infants surveyed, prematurity was the most prevalent risk factor, followed by perinatal asphyxia. Low birth weight was observed in 43% of cases, while hyperbilirubinemia and neonatal sepsis were the next. Among the 70 infants assessed, 50% were found to have normal hearing. Mild hearing loss was observed in 23% of cases, while 14% had moderate hearing loss. Severe and profound hearing loss were less common.

Conclusion

Our study highlighted the importance of early and routine auditory screening using BERA in high-risk neonates and infants, revealing a significant prevalence of hearing loss linked to various risk factors such as premature babies, low birth weight, hyperbilirubinemia, neonatal intensive care unit stay, perinatal asphyxia, and ototoxic drugs during pregnancy. Prematurity is the most common risk factor. For language development, early diagnosis and intervention were crucial. If babies have profound sensorineural hearing loss, they can go for a cochlear implant.

## Linked entities

- **Diseases:** hearing impairment (MONDO:0005365), perinatal asphyxia (MONDO:0006663), hyperbilirubinemia (MONDO:0002408), neonatal sepsis (MONDO:0700217)

## Full-text entities

- **Diseases:** neonatal sepsis (MESH:D000071074), Hearing impairment (MESH:D034381), sensorineural hearing loss (MESH:D006319), ototoxic medications (MESH:D006311), ototoxic drugs (MESH:D000081015), hyperbilirubinemia (MESH:D006932), Prematurity (MESH:C536271), perinatal asphyxia (MESH:D001237)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11393516/full.md

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Source: https://tomesphere.com/paper/PMC11393516