# Unusual Radiological Presentation of a Typical Carcinoid in a Young Female With High-Grade Intermittent Fever: A Case Report

## TL;DR

A young woman presented with unusual symptoms of fever and breathing issues, later diagnosed with a rare lung tumor called typical carcinoid.

## Contribution

This case report highlights an atypical clinical and radiological presentation of a typical pulmonary carcinoid tumor.

## Key findings

- The patient exhibited high-grade intermittent fever and respiratory symptoms, which are uncommon for typical carcinoids.
- Radiological imaging showed a homogenously enhancing lesion, leading to a biopsy confirming a Grade 1 neuroendocrine tumor.
- The diagnosis was supported by immunohistochemical markers Synaptophysin and Chromogranin A.

## Abstract

Pulmonary carcinoids, particularly the typical variant, are low-grade neuroendocrine tumors (NETs) known for their often indolent behavior. Their rare and atypical presentations can pose significant diagnostic challenges. We present a case of a 39-year-old female with no significant past medical history who presented with high-grade intermittent fever, chills, rigors, and breathlessness, with symptoms persisting for approximately 20 days. Initial investigations, including chest X-ray and contrast-enhanced computed tomography scans, revealed a homogenously enhancing lesion in the left lower lobe, raising concerns of a malignant process. A percutaneous lung biopsy was performed to further evaluate the lesion. Histopathological examination confirmed a diagnosis of Grade 1 NET (typical carcinoid), supported by elevated levels of Synaptophysin and Chromogranin A on immunohistochemistry. This case highlights the varied clinical presentations of pulmonary carcinoid tumors and underscores the importance of comprehensive radiological and histopathological assessments for accurate diagnosis and effective management.