# Unraveling the Puzzle: A Case of Intricate Neurological Presentation Attributable to Hypomagnesemia

**Authors:** Syed H Hussain, Mohammed Zaidi, Mariam Zaidi, Guy M Grabau

PMC · DOI: 10.7759/cureus.69273 · Cureus · 2024-09-12

## TL;DR

This paper presents a rare case where severe neurological symptoms were caused by low magnesium levels without an obvious underlying condition.

## Contribution

The novelty lies in highlighting hypomagnesemia as a primary cause of neurological deficits without typical renal or gastrointestinal pathology.

## Key findings

- A 48-year-old male presented with severe neurological symptoms due to hypomagnesemia.
- No renal, gastrointestinal, hormonal, infectious, or autoimmune pathology was found.
- The case emphasizes the need to consider hypomagnesemia in ICU neurological presentations.

## Abstract

Hypomagnesemia can occasionally present with severe neurological deficiencies, and it is usually attributed to an underlying renal and/or gastrointestinal pathology. Rarely, patients may present with neurological symptoms in the absence of an obvious cause. Our case highlights the importance of considering hypomagnesemia as a primary cause of those presenting with severe neurological deficits in an intensive care unit setting, as well as the significance of conducting a thorough social and medical history on these patients to elucidate their underlying causes. We discuss the case of a 48-year-old Caucasian male who acutely presented with seizures, tremors, visual hallucinations, diplopia, personality changes, and ataxia with recurring severely low magnesium (0.4 mg/dL) at times in the absence of renal, gastrointestinal, hormonal, infectious, or autoimmune pathology.

## Linked entities

- **Chemicals:** magnesium (PubChem CID 5462224)
- **Diseases:** hypomagnesemia (MONDO:0018100), ataxia (MONDO:0000437)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** Hypomagnesemia (OMIM:613882), ataxia (MESH:D001259), neurological deficiencies (MESH:D009461), tremors (MESH:D014202), renal (MESH:D006030), gastrointestinal (MESH:D005767), autoimmune (MESH:D001327), seizures (MESH:D012640), diplopia (MESH:D004172), visual hallucinations (MESH:D006212), changes (MESH:D009402)
- **Chemicals:** magnesium (MESH:D008274)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11392027/full.md

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Source: https://tomesphere.com/paper/PMC11392027