Cone-Beam Computed Tomography-Guided Adaptive Radiotherapy: A Case Report on Dynamic Tumor Response in Lung Adenocarcinoma

TL;DR

This case report shows how cone-beam CT helps adjust radiation therapy for lung cancer by tracking tumor changes and improving treatment accuracy.

Contribution

The paper demonstrates the practical benefits of CBCT-guided adaptive radiotherapy in a lung adenocarcinoma case.

Findings

CBCT monitoring revealed significant tumor shrinkage during treatment.

Adaptive replanning improved targeting while reducing radiation to healthy tissues.

The treatment achieved excellent outcomes without complications.

Abstract

Cone-beam computed tomography (CBCT) is an essential tool in radiotherapy, enhancing patient positioning accuracy and enabling precise treatment delivery by monitoring anatomical changes throughout the treatment process. This case report highlights the significant role of CBCT in managing a patient with lung adenocarcinoma treated with concurrent chemoradiation. The lung mass and lower paratracheal lymph nodes were irradiated with 60 Gy in 30 fractions. During the course of treatment, CBCT allowed us to observe substantial tumor shrinkage, prompting a treatment replanning to ensure optimal targeting of the tumor while minimizing radiation exposure to healthy tissues. This adaptive approach resulted in excellent treatment outcomes with no complications, demonstrating the efficacy of CBCT in modern radiotherapy.

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