# Erythema Scarlatiniforme Desquamativum Recidivans: A Rare and Puzzling Condition

**Authors:** Ghita Benbrahim Ansari, Houda Naji, Hanan Aboufaris, Kenza Bouayed

PMC · DOI: 10.7759/cureus.68981 · 2024-09-09

## TL;DR

This paper describes a rare skin condition called erythema scarlatiniforme desquamativum recidivans in a young girl, aiming to raise awareness among doctors.

## Contribution

The paper presents a rare case of ESDR in a 13-year-old, highlighting its benign nature and diagnostic challenges.

## Key findings

- ESDR can occur in children, contrary to most cases being in older adults.
- The condition is marked by recurrent rashes and desquamation, often with prodromal symptoms.
- Physicians should consider ESDR in differential diagnoses to avoid misdiagnosis.

## Abstract

Recurrent erythema scarlatiniforme desquamativum recidivans (ESDR), also known as Féréol-Besnier disease, is a rare condition marked by a recurrent erythematous rash that is followed by extensive desquamation, primarily affecting the palms and soles. It is often preceded by prodromal symptoms such as malaise, headache, myalgias, digestive issues, and fever. The exact pathogenesis remains unknown, and diagnosis can be challenging due to its resemblance to various infectious, auto-inflammatory, or allergic conditions, leading to diagnostic variability. Given that most reported cases are over 50 years old, our objective is to highlight this rare and enigmatic pathology through a typical case of the generalized variant of ESDR in a 13-year-old girl. We aim to increase physician awareness of this condition and provide reassurance to both parents and their child regarding its benign nature.

## Full-text entities

- **Diseases:** allergic conditions (MESH:D004342), erythematous rash (MESH:D005076), auto-inflammatory (MESH:D018467), fever (MESH:D005334), headache (MESH:D006261), desquamation (MESH:D017490), myalgias (MESH:D063806), ESDR (MESH:C535512), infectious (MESH:D003141), Fereol-Besnier disease (MESH:D012507), Puzzling Condition (MESH:D020763)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11390138/full.md

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Source: https://tomesphere.com/paper/PMC11390138