Correction: Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms
Jessica Wagner, C. Leah Kline, Lanlan Zhou, Vladimir Khazak, Wafik S. El-Deiry
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCancer, Hypoxia, and Metabolism · Cancer Treatment and Pharmacology · Angiogenesis and VEGF in Cancer
Correction: J Exp Clin Cancer Res 37, 11 (2018)
https://doi.org/10.1186/s13046-018-0671-0
Following publication of the original article [1], the authors have been alerted to an error in Fig. 3A that shows a duplication of a histological image in two panels in the figure. This image duplication error in Fig. 3A was missed by all the authors and reviewers of the paper.
Incorrect Fig. 3 Fig. 3ONC201 does not impact VEGF expression in xenografts or HUVEC sprouting. a VEGF-A expression as detected by immunohistochemistry in HT29 and HCT116 CRC xenografts. b HUVEC representative images of sprouting from HUVECs grown on Matrigel. c Quantitation of HUVEC sprouting and branching after 12 h of drug treatment. In vivo: n = 5 ONC201 treatment dose was 50 mg/kg weekly. HUVECS N = 4, ONC201 treatment dose 5 μM, bevacizumab dose 5 mg/ml
Correct Fig. 3 Fig. 3ONC201 does not impact VEGF expression in xenografts or HUVEC sprouting. a VEGF-A expression as detected by immunohistochemistry in HT29 and HCT116 CRC xenografts. b HUVEC representative images of sprouting from HUVECs grown on Matrigel. c Quantitation of HUVEC sprouting and branching after 12 h of drug treatment. In vivo: n = 5 ONC201 treatment dose was 50 mg/kg weekly. HUVECS N = 4, ONC201 treatment dose 5 μM, bevacizumab dose 5 mg/ml