# Two-dimensional Graphene/MoS2 vertical heterostructure for detection of hemoglobin concentration in blood samples

## TL;DR

Researchers designed a flexible graphene/MoS2 structure to detect hemoglobin in blood samples using computational simulations.

## Contribution

A novel non-invasive hemoglobin sensing platform using a Graphene/MoS2 heterostructure is proposed and computationally validated.

## Key findings

- The heterostructure shows a significant shift in refractive index and extinction coefficient with varying hemoglobin concentrations.
- Maximum spectral response occurs at approximately 600 nm, indicating optimal detection potential.
- The structure is sensitive to hemoglobin concentrations in the range of 0.3 μm to 1 μm.

## Abstract

This study demonstrates the use of computational methods to simulate the molecular dynamics involved in hemoglobin concentration sensing, utilizing Material Studio and the TCAD Silvaco device simulator. A non-invasive and flexible Graphene/MoS2 heterostructure has been proposed for sensing hemoglobin concentration in blood samples. The findings reveal a notable shift in the wavelength-dependent refractive index and extinction coefficient, as well as significant changes in the absorption coefficient and reflectivity of the Graphene/MoS2 heterostructure in response to different hemoglobin concentrations, specifically within an approximate range of 0.3 μm to 1 μm. Moreover, the spectral response of the heterostructure demonstrates that at a particular wavelength of approximately 600 nm, a maximum response is obtained. This wavelength can be considered optimal for detecting various levels of hemoglobin using this heterostructure. The anticipated outcome is a comprehensive understanding of the fundamental principles, ultimately resulting in the development of an exceptionally sensitive platform for detecting hemoglobin concentration.