# Complete coding sequence of Rift Valley fever virus identified by metagenomic sequencing in patient with undifferentiated febrile illness at Marigat sub-district hospital, Kenya

**Authors:** Allan Lemtudo, Gathii Kimita, George Awinda, Beth Mutai, John Waitumbi

PMC · DOI: 10.1128/mra.00366-24 · Microbiology Resource Announcements · 2024-07-31

## TL;DR

Scientists identified the full genetic code of Rift Valley fever virus in a child's blood sample using metagenomic sequencing in Kenya.

## Contribution

The study reports the complete coding sequence of Rift Valley fever virus identified through metagenomic sequencing in a clinical setting.

## Key findings

- The virus's genome clustered phylogenetically with sequences from the 2017 Uganda and 2021 Kiambu outbreaks.
- Metagenomic sequencing successfully identified the virus in a patient with undifferentiated fever.

## Abstract

We report on the complete coding sequence of Rift Valley Fever Virus inadvertently identified through metagenomics in a child with undifferentiated fever at Marigat sub-county hospital, Kenya. On phylogeny, the genome clustered with sequences obtained during the 2017 human outbreak in Uganda and the 2021 cattle outbreak in Kiambu, Kenya.

## Linked entities

- **Diseases:** Rift Valley fever (MONDO:0017880)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** undifferentiated fever (MESH:D005334), undifferentiated febrile illness (MESH:C580334)
- **Species:** Rift Valley fever virus (no rank) [taxon 11588], Homo sapiens (human, species) [taxon 9606], Bos taurus (bovine, species) [taxon 9913]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11385453/full.md

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Source: https://tomesphere.com/paper/PMC11385453