# Genome sequences of Clostridium perfringens isolated from diseased dogs

**Authors:** Camilla Sekse, Helene K. Solsvik, Thomas H. A. Haverkamp, Håkon Kaspersen, Wenche S. Gulliksen, Sabrina R. Campos, Simen F. Nørstebø, Cathrine A. Bøe

PMC · DOI: 10.1128/mra.00244-24 · Microbiology Resource Announcements · 2024-08-20

## TL;DR

This paper reports the genome sequences of two Clostridium perfringens isolates from dogs with acute diarrhea.

## Contribution

The study provides closed genome sequences and identifies virulence genes in C. perfringens isolates from diseased dogs.

## Key findings

- Hybrid assemblies using Illumina and Oxford Nanopore sequencing were generated.
- One genome was fully closed, and virulence genes were identified in both isolates.

## Abstract

Two Clostridium perfringens isolates originating from two Norwegian dogs with acute hemorrhagic diarrhea were sequenced. Based on Illumina and Oxford Nanopore Technology sequencing, hybrid assemblies were generated, and one of the genomes was completed and closed. For both isolates, virulence genes and their genomic location have been identified.

## Linked entities

- **Species:** Clostridium perfringens (taxon 1502), Canis lupus familiaris (taxon 9615)

## Full-text entities

- **Diseases:** hemorrhagic diarrhea (MESH:D003967)
- **Species:** Clostridium perfringens (species) [taxon 1502], Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11385440/full.md

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Source: https://tomesphere.com/paper/PMC11385440