# Effect of Brazilian green propolis in chronic ulcer treatment: a randomized clinical trial

## TL;DR

This study found that a 5% Brazilian green propolis ointment may be more effective than essential fatty acid treatment for healing chronic ulcers after 30 days.

## Contribution

Demonstrates the superior healing effectiveness of Brazilian green propolis ointment in chronic ulcer treatment through a randomized clinical trial.

## Key findings

- The experimental group showed greater improvement in tissue type, exudate, edge characteristics, microbial content, and pain.
- Both groups showed healing effects, but propolis was more effective.
- No significant sociodemographic or baseline clinical differences were found between groups.

## Abstract

to assess the effectiveness of 5% Brazilian green propolis (ointment) in individuals with chronic ulcers.

a randomized clinical trial, developed with 40 patients randomized equally to control group (treated with essential fatty acid) and experimental group (treated with 5% green propolis) for 30 days. The outcomes of interest were sociodemographic, clinical and laboratory characteristics, lesion characteristics, such as type of tissue in the bed, presence of exudate, edge characteristics, microbial content and pain.

regarding sociodemographic, clinical and laboratory characteristics, the two groups did not show statistically significant differences. After assessment in 30 days, an effect was observed for both treated groups, but for the experimental group, greater effectiveness in terms of the type of tissue in the bed, type of exudate, edge characteristics, microbial content and pain.

propolis-based ointment showed a healing effect, presenting itself as a potential tool in healing chronic ulcers.

avaliar a eficácia da própolis verde brasileira a 5% (pomada) em indivíduos com úlceras crônicas.

ensaio clínico randomizado, desenvolvido com 40 pacientes aleatorizados igualmente para grupo controle (tratado com ácido graxo essencial) e grupo experimental (tratado com própolis verde a 5%) por 30 dias. Os desfechos de interesse foram características sociodemográficas, clínicas e laboratoriais, características das lesões, como tipo de tecido no leito, presença de exsudato, características da borda, conteúdo microbiano e dor.

quanto às características sociodemográficas, clínicas e laboratoriais, os dois grupos não apresentaram diferença estatisticamente significativas. Após avaliação em 30 dias, observou-se efeito para os dois grupos tratados, porém, para o grupo experimental, maior eficácia quanto ao tipo de tecido no leito, tipo de exsudato, característica da borda, conteúdo microbiano e dor.

a pomada a base de própolis mostrou efeito cicatrizante, apresentando-se como potencial instrumento na cicatrização de úlceras crônicas.