# Unilateral Vogt-Koyanagi-Harada Disease With Two Distinct Choroidal Neovascular Membranes: A Case Report

## TL;DR

This case report describes a rare instance of unilateral Vogt-Koyanagi-Harada disease with two distinct choroidal neovascular membranes and uveitis reactivation.

## Contribution

The novelty lies in documenting a rare unilateral VKH case with two distinct choroidal neovascular membranes and successful treatment outcomes.

## Key findings

- The patient presented with two distinct choroidal neovascular membranes.
- Treatment with systemic and intravitreal agents led to a good clinical response.
- Reactivation of posterior uveitis occurred twice during treatment.

## Abstract

Vogt-Koyanagi-Harada (VKH) disease is a multisystem inflammatory disease that usually presents with bilateral panuveitis. Unilateral manifestations of VKH, albeit rare, have been described. Choroidal neovascularization may occur as a complication during the disease. Reactivation of uveitis may also occur during treatment.

A patient with unilateral features of VKH disease presented with two distinct types of choroidal neovascular membranes and two episodes of reactivation of posterior uveitis. He underwent treatment with a combination of systemic steroids/immunosuppressive agents, intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents, and dexamethasone implants with good clinical response.

Patients with VKH disease need to be diagnosed early, treated adequately with a combination of systemic and ocular medication, and followed up diligently for any complication that may arise, to optimize visual acuity.