# Genomic-Based Early Detection Screening: A Literature Review of Prospective Trials and Emerging Strategies for Gastrointestinal Cancers

## TL;DR

This paper reviews genomic-based screening tests for early detection of gastrointestinal cancers and their potential to improve current screening methods.

## Contribution

The paper highlights the performance of genomic-based tests in prospective trials and outlines new strategies for gastroenterologists.

## Key findings

- Genomic-based tests show promise in early detection of gastrointestinal cancers.
- Prospective clinical trials demonstrate the effectiveness of these tests.
- New strategies are emerging for diagnosing individuals with cancer signals.

## Abstract

Numerous genomic-based early detection screening tests are being developed. These tests have the potential to revolutionize current single-organ screening paradigms, especially in gastrointestinal cancers. In this review, we underscore the performance of these genomic-based early detection tests based on prospective clinical trials. Moreover, we discuss a professional advancement for gastroenterologists in the diagnostic assessment of individuals who are cancer signal positive.