# Injection Depot Medroxyprogesterone Acetate as an Early Postpartum Contraceptive Measure: Evaluation of Its Acceptability, Efficacy, and Impact on Lactation

**Authors:** Sonal Srivastava Garg, Bhavna Bhateja, Seema Grover, Isha Tapasvi

PMC · DOI: 10.7759/cureus.66454 · 2024-08-08

## TL;DR

This study shows that DMPA is a safe and effective postpartum contraceptive that does not harm breastfeeding, though more education is needed to improve its continued use.

## Contribution

The study evaluates DMPA's efficacy, acceptability, and impact on lactation in early postpartum Indian women.

## Key findings

- DMPA was 100% effective as a postpartum contraceptive.
- 99% of patients reported satisfaction with their lactation.
- Continuation rate for the second dose was only 18%, indicating a need for better counseling.

## Abstract

Introduction

Through its National Family Planning Programme, India has been relentlessly working to decrease society’s unmet contraception needs. The postpartum period is of paramount importance for addressing these contraceptive needs owing to alterations in fertility and coital behavior associated with childbirth.

Depot medroxyprogesterone acetate (DMPA), a long-acting reversible contraceptive, is one of the safe options available in the early postpartum period. In this study, we aimed to evaluate its efficacy and acceptability among postpartum women delivering in Guru Gobind Singh Medical College and Hospital.

Methodology

We recruited 206 early postpartum women for the study. After thorough counseling and ensuring establishment of lactation, we administered DMPA 150mg by injection intramuscularly and repeated it at intervals of three months in willing patients. We then evaluated them for their symptoms, side effects, and lactation status using a predesigned proforma either during their follow-up visits or telephonically.

Results

We found DMPA to be 100% efficacious as an early postpartum contraceptive measure. The main reasons for acceptance were its ease of use, long-term effects of a single dose, and noninterference with lactation.

However, the continuation rate for the second dose was only 18% in our study, highlighting the need for better counseling and improving awareness among our patients. Ninety-nine percent of our patients were satisfied with their lactation.

Conclusion

We found injectable DMPA used as a contraceptive in the immediate postpartum period to be a safe and effective alternate method with no deleterious effect on lactation and an acceptable side effect profile. However, more awareness programs are necessary to encourage women, especially those in low-resource areas, to continue using DMPA.

## Linked entities

- **Chemicals:** Depot medroxyprogesterone acetate (PubChem CID 6279)

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11380525/full.md

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Source: https://tomesphere.com/paper/PMC11380525