Advancing Research on Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors: A Scientometric Analysis
Abdul Matin, Gul-e-Saba Chaudhry, Mohamad Nor Azra, Mohamad Gazali, Yik Sung Yeong, Tengku Sifzizul Tengku Muhammad
TL;DR
This paper analyzes global research trends on PCSK9 inhibitors for treating atherosclerosis using scientometric methods.
Contribution
It presents the first comprehensive scientometric analysis of PCSK9 inhibitors research from 2008 to 2022.
Findings
885 publications on PCSK9 inhibitors were analyzed from 2008 to 2022.
Lipid-lowering therapy and bempedoic acid are key research clusters.
Sabatine et al. and The New England Journal of Medicine are most impactful.
Abstract
Atherosclerosis is characterised by the accumulation of fatty deposits and plaque as a result of a continuously high level of low-density lipoprotein cholesterol (LDL-C) in the blood. The primary objective of this research is to assess the current status of knowledge, research endeavours and developmental trajectories about proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in correlation with atherosclerosis treatment. Additionally, this study aims to compile bibliometric and scientometric investigations within this domain through rigorous scientometric analysis. Analysing the bibliometric landscape and global research trends associated with PCSK9 inhibitors can contribute valuable insights into comprehending atherosclerosis. This is exemplified by examining publications within the Web of Science Core Collection (WOSCC) database from 2008 to 2022. Citespace was used for…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsEnzyme Production and Characterization · Enzyme Structure and Function · Biochemical and Molecular Research