# A Rare Case of Primary Squamous Cell Carcinoma of the Stomach: A Case Report

**Authors:** Abby Kunitsky, Gautam Maddineni, Julia Janecki, Edward Jurkovic, Vladimir Ferrer

PMC · DOI: 10.7759/cureus.66220 · 2024-08-05

## TL;DR

This paper reports a rare case of stomach cancer that is primarily squamous cell carcinoma and discusses its challenges in diagnosis and treatment.

## Contribution

The paper presents a rare clinical case of primary gastric squamous cell carcinoma and reviews its management strategies.

## Key findings

- A 51-year-old woman presented with a 7.6 cm necrotic mass in the proximal stomach and metastasis.
- PGSCC lacks standardized treatment protocols, requiring further research for better outcomes.

## Abstract

Pure primary gastric squamous cell carcinoma (PGSCC) is a notably rare gastric malignancy. We present the case of a 51-year-old woman with advanced gastric squamous cell carcinoma characterized by a 7.6 cm necrotic mass invading the proximal stomach, liver metastasis, and lymphadenopathy at diagnosis. Despite the lack of standardized treatment protocols, we review tumor markers and potential management strategies, including surgical and chemotherapeutic interventions. The rarity and aggressive nature of PGSCC necessitates further research to develop effective detection and treatment methods to improve patient prognosis and survival outcomes.

## Linked entities

- **Diseases:** gastric squamous cell carcinoma (MONDO:0006230), lymphadenopathy (MONDO:0005833)

## Full-text entities

- **Diseases:** necrotic mass (MESH:C536030), gastric malignancy (MESH:D013274), lymphadenopathy (MESH:D008206), liver metastasis (MESH:D009362), tumor (MESH:D009369), PGSCC (MESH:D002294)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11374448/full.md

---
Source: https://tomesphere.com/paper/PMC11374448