# Amyloid Goiter in a 57-Year-Old Woman With Chronic Kidney Disease: A Case Report

**Authors:** A. Rahman Farahat, Mahera Roohi

PMC · DOI: 10.7759/cureus.66167 · 2024-08-05

## TL;DR

A 57-year-old woman with chronic kidney disease was found to have amyloid goiter, a rare condition where amyloid proteins accumulate in the thyroid.

## Contribution

This case report highlights amyloid goiter as a rare initial manifestation of amyloidosis in a patient with pre-existing kidney disease.

## Key findings

- Amyloid goiter was diagnosed in a patient with a history of renal failure.
- The case illustrates the potential for amyloid proteins to affect multiple organs, including the thyroid and kidneys.

## Abstract

Amyloid goiter (AG) is a condition in which amyloid protein builds up in the thyroid gland. Patients with such a condition tend to have thyroid tissue that is extensively involved by amyloid; however, patients are usually euthyroid. Systemic amyloidosis is one of the conditions that may cause damage to the kidneys or worsen the condition of kidney failure in patients with ongoing chronic kidney disease as amyloid proteins can deposit in a variety of tissues including kidneys. Thyroid goiter can rarely be the first confirmed place to be involved with amyloidosis. We present the case of a 57-year-old female with AG who had a history of renal failure.

## Linked entities

- **Diseases:** chronic kidney disease (MONDO:0005300), renal failure (MONDO:0001106)

## Full-text entities

- **Diseases:** amyloidosis (MESH:D000686), kidney failure (MESH:D051437), amyloid (MESH:C000718787), AG (MESH:D006042), Chronic Kidney Disease (MESH:D051436), to the kidneys (MESH:D007674), Systemic amyloidosis (MESH:D009101)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11372726/full.md

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Source: https://tomesphere.com/paper/PMC11372726