# Bronchoscopic Interventional Therapy Combined With Pembrolizumab in the Treatment of Pulmonary Large Cell Neuroendocrine Carcinoma: A Case Report

**Authors:** Yingyi Fan, Yingying Wang, Yanrong Ji, Shuang Li, Jian Zhang, Xingliang Hao

PMC · DOI: 10.1111/crj.70009 · The Clinical Respiratory Journal · 2024-09-03

## TL;DR

A new treatment combining bronchoscopy and pembrolizumab showed promising results in a rare and aggressive lung cancer case.

## Contribution

Combining bronchoscopic therapy with pembrolizumab offers a novel treatment strategy for pulmonary large cell neuroendocrine carcinoma.

## Key findings

- The combination therapy led to significant clinical improvement in a patient with LCNEC.
- This approach demonstrates potential for managing this aggressive form of lung cancer.

## Abstract

This study reports a significant clinical outcome following the use of bronchoscopic interventional therapy combined with pembrolizumab for treating pulmonary large cell neuroendocrine carcinoma (LCNEC), showcasing a novel approach in managing this aggressive cancer.

Bronchoscopic interventional therapy combined with pembrolizumab in the treatment of Large cell neuroendocrine carcinoma of the lung has achieved good results.

## Linked entities

- **Diseases:** pulmonary large cell neuroendocrine carcinoma (MONDO:0003960), LCNEC (MONDO:0005057)

## Full-text entities

- **Diseases:** LCNEC (MESH:D018287), cancer (MESH:D009369)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11370624/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11370624/full.md

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Source: https://tomesphere.com/paper/PMC11370624