# Comparative analysis of central aortic blood pressure, pulse wave velocity & arterial stiffness in patients with obstructive airway disease

## TL;DR

This study compares arterial stiffness and blood pressure in Indian patients with COPD and asthma, finding higher values in COPD patients.

## Contribution

The study provides new comparative data on arterial stiffness and central hemodynamics in COPD and asthma patients in India.

## Key findings

- PWV, AI, and VA were significantly higher in COPD patients compared to asthma patients.
- COPD patients showed increased arterial stiffness even without cardiac comorbidities.
- The study highlights the cardiovascular risk differences between obstructive airway diseases.

## Abstract

As the pulmonary system and cardiovascular system are intimately linked, patients with chronic obstructive pulmonary disease (COPD) and asthma have high risk for developing cardiovascular diseases (CVDs) and altered central hemodynamic.

We aim to assess the central aortic blood pressure (CABP) indices, pulse wave velocity (PWV) and other indicators of arterial stiffness in Indian patients with COPD and bronchial asthma.

This is a single‐center, cross‐sectional study conducted in outpatients diagnosed with either chronic stable phase of COPD or bronchial asthma. CABP indices, vascular age, arterial stiffness and central hemodynamics were measured in patients.

Of 193 patients with obstructive airway disease who were enrolled, (n = 81 had COPD and n = 112 had partially‐controlled bronchial asthma) the proportion of male patients was higher in both groups. The PWV, augmentation index (AI) and vascular age (VA) were significantly higher in patients with COPD compared to those with bronchial asthma (all, p < 0.05).

The study showed that PWV, AI and VA were higher in patients with stable COPD without any cardiac comorbidities compared to bronchial asthma.