# Factors influencing the performance of organocatalysts immobilised on solid supports: A review

**Authors:** Zsuzsanna Fehér, Dóra Richter, Gyula Dargó, József Kupai

PMC · DOI: 10.3762/bjoc.20.183 · Beilstein Journal of Organic Chemistry · 2024-08-26

## TL;DR

This review discusses how different factors affect the performance of organocatalysts attached to solid supports, aiming to improve their reusability and efficiency in chemical reactions.

## Contribution

The paper systematically reviews key parameters influencing the effectiveness of immobilized organocatalysts, offering insights for optimizing their performance.

## Key findings

- The type of support material significantly impacts the catalytic activity and recyclability of immobilized organocatalysts.
- Immobilization techniques influence the interactions between the catalyst and the support, affecting selectivity and reusability.
- Optimizing immobilization strategies can enhance the practical application of organocatalysts in organic chemistry.

## Abstract

Organocatalysis has become a powerful tool in synthetic chemistry, providing a cost-effective alternative to traditional catalytic methods. The immobilisation of organocatalysts offers the potential to increase catalyst reusability and efficiency in organic reactions. This article reviews the key parameters that influence the effectiveness of immobilised organocatalysts, including the type of support, immobilisation techniques and the resulting interactions. In addition, the influence of these factors on catalytic activity, selectivity and recyclability is discussed, providing an insight into optimising the performance of immobilised organocatalysts for practical applications in organic chemistry.

## Full-text entities

- **Chemicals:** squaramide (MESH:C000609819), cinchona alkaloid (MESH:D002930), Polymer (MESH:D011108), oleic acid (MESH:D019301), dendrimer (MESH:D050091), sulfonamide (MESH:D013449), lactose (MESH:D007785), prolinamide (MESH:C056291), hydrogen (MESH:D006859), PS (MESH:D011137), propylsulfonic acid (MESH:C068559), hydrocarbon (MESH:D006838), silica gel (MESH:D058428), COF (MESH:D000073396), di-tert-butyl azodicarboxylate (MESH:C572223), quinuclidine (MESH:D011812), sorbitol (MESH:D013012), proline (MESH:D011392), MCM-41 (MESH:C509968), Silica (MESH:D012822), pyrrolidone (MESH:D011760), mannitol (MESH:D008353), propanal (MESH:C005556), polyamide (MESH:D009757), PGMA (MESH:C042535), Benzoin (MESH:D001573), MOFs (MESH:C040750), methanol (MESH:D000432), cinchonidine (MESH:C041622), chalcone (MESH:D002599), trans-beta-nitrostyrene (MESH:C011955), nitromethane (MESH:C008640), n-butyl acrylate (MESH:C032490), potassium chloride (MESH:D011189), water (MESH:D014867), metal (MESH:D008670), chitosan (MESH:D048271), pentane-2,4-dione (MESH:C008790), SBA-15 (MESH:C509969), amine (MESH:D000588), polystyrene-divinylbenzene (MESH:C003771), piperazine (MESH:D000077489), ethyl 2-oxocyclopentanecarboxylate (MESH:C506754), triethylamine (MESH:C016162), dimethyl malonate (MESH:C005230), betaine (MESH:D001622), thiourea (MESH:D013890), epoxy (MESH:D004853), resin (MESH:D012116), xylitol (MESH:D014993), glycerol (MESH:D005990), C29-C31 (-), PMHS (MESH:C402373)

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11368055/full.md

## References

132 references — full list in the complete paper: https://tomesphere.com/paper/PMC11368055/full.md

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Source: https://tomesphere.com/paper/PMC11368055