# Portal Hypertension in Children: Investigating Umbilical Catheterization in the Neonatal Period

**Authors:** Nadia Bouhafs, Amal Hamami, Aziza Elouali, Abdeladim Babakhouya, Maria Rkain

PMC · DOI: 10.7759/cureus.66060 · Cureus · 2024-08-03

## TL;DR

This paper discusses how umbilical catheterization in newborns can lead to serious liver-related complications in children, such as portal hypertension and life-threatening bleeding.

## Contribution

The paper highlights a rare but severe complication of neonatal umbilical catheterization through a case report.

## Key findings

- Neonatal umbilical catheterization can cause portal vein thrombosis and portal hypertension.
- A five-year-old child experienced upper GI bleeding due to ruptured esophageal varices from a portal cavernoma.
- The case emphasizes the risk of vascular complications from umbilical vein catheterization in newborns.

## Abstract

Portal cavernoma is a major cause of extrahepatic portal hypertension (EHPH) in children. It is a serious condition, due to the frequency and severity of digestive hemorrhages secondary to the rupture of esophageal varices (EV). Neonatal umbilical catheterization is a significant risk factor for the development of portal vein thrombosis (PVT) and portal hypertension. We report a case of a five-year-old male who presented with upper gastrointestinal (GI) bleeding on ruptured esophageal varices resulting from a portal cavernoma, complicating neonatal umbilical vein catheterization. This case illustrates the risk of severe vascular complications, particularly portal hypertension that can result from neonatal umbilical vein catheterization.

## Linked entities

- **Diseases:** portal hypertension (MONDO:0005080), esophageal varices (MONDO:0001221), portal vein thrombosis (MONDO:0001339)

## Full-text entities

- **Diseases:** rupture (MESH:D012421), EHPH (MESH:D006975), EV (MESH:D004932), vascular complications (MESH:D003925), hemorrhages (MESH:D006470), PVT (MESH:D012170), upper gastrointestinal (GI) bleeding (MESH:D006471)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11367683/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11367683/full.md

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Source: https://tomesphere.com/paper/PMC11367683