# Virucidal activity of chlorine dioxide in combination with acetic acid or citric acid and a surfactant, in presence of interfering substances, against polio-, adeno- and murine norovirus in suspension-, carrier- and four-field tests

## TL;DR

This study shows that chlorine dioxide combined with acids and surfactants effectively kills viruses like polio and norovirus even in the presence of interfering substances.

## Contribution

The study demonstrates the enhanced virucidal effectiveness of chlorine dioxide when combined with carboxylic acids and surfactants.

## Key findings

- Chlorine dioxide with acetic or citric acid and surfactants is effective against polio-, adeno-, and norovirus.
- The virucidal activity was tested in suspension, carrier, and four-field tests with interfering substances.
- Three disinfectant formulations showed activity after 5 minutes of exposure.

## Abstract

The aim of the study was to investigate whether the virucidal effectiveness of chlorine dioxid against adenovirus and murine norovirus can be improved by combining it with carboxylic acids and surfactants.

The virucidal efficacy against polio-, adeno- and murine norovirus has been tested in presence of interfering substances in the quantitative suspension test according to EN 14476, the carrier test without mechanical action according to EN 16777, and in the four-field test according to EN 16615.

Three chlorine-dioxide-based surface disinfectants were tested: a two-component cleaning disinfectant concentrate for large surfaces, a ready-to-use (RTU) foam, and an RTU gel.

Cleaning and disinfecting preparations based on chlorine dioxide, applied at various concentrations, in combination with acetic acid or citric acid and surfactants, are virucidally active against polio-, adeno-, and norovirus after an exposure time of 5 minutes in presence of interfering substances.