# Unveiling the Uncommon: A Case Series on Cushing’s Disease During Pregnancy

**Authors:** Ravi Shah, Subin S, Vanita Suri, Sanjay K Bhadada, Rama Walia

PMC · DOI: 10.7759/cureus.66045 · Cureus · 2024-08-02

## TL;DR

This paper presents three cases of Cushing's disease that were likely missed during pregnancy due to overlapping symptoms with normal pregnancy changes.

## Contribution

The paper introduces a case series highlighting the challenges of diagnosing Cushing's disease during pregnancy.

## Key findings

- CD symptoms often overlap with normal pregnancy changes, leading to potential misdiagnosis.
- Three cases of CD were likely missed during pregnancy and diagnosed later.
- The paper discusses approaches to diagnosing and managing CD during pregnancy.

## Abstract

Cushing's disease (CD) is characterized by a high rate of hypogonadism and infertility. It is difficult to detect CD in pregnant women who present with symptoms such as weight gain, striae, headache, backache, and pedal edema that overlap with the physiological changes of pregnancy. In this paper, we present three cases of CD likely missed during pregnancy and later also discuss the approach to diagnosis and management of CD in pregnancy.

## Linked entities

- **Diseases:** Cushing's disease (MONDO:0009050)

## Full-text entities

- **Diseases:** backache (MESH:D001416), hypogonadism (MESH:D007006), headache (MESH:D006261), weight gain (MESH:D015430), infertility (MESH:D007246), striae (MESH:D057896), pedal edema (MESH:D004487), CD (MESH:D047748)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11366835/full.md

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Source: https://tomesphere.com/paper/PMC11366835