# Monoclonal Gammopathy of Renal Significance With Preexisting Connective Tissue Disease: A Case Report

## TL;DR

This case report describes a patient with monoclonal gammopathy of renal significance and a preexisting connective tissue disease, highlighting successful treatment through a multidisciplinary approach.

## Contribution

The novelty lies in presenting a rare case of MGRS co-occurring with a connective tissue disease and demonstrating effective multidisciplinary management.

## Key findings

- A patient with MGRS and connective tissue disease was successfully treated with a multidisciplinary approach.
- Early detection and collaboration among specialists led to an accurate diagnosis and effective treatment.
- Renal biopsy and hematological studies were crucial in confirming the nephropathological diagnosis.

## Abstract

Monoclonal gammopathy of renal significance (MGRS) has lately drawn the interest of physicians and pathologists due to the ability of these monoclonal proteins to cause end-organ damage. The early detection of this monoclonal protein along with hematological studies and renal biopsy are essential to establish the associated nephropathological diagnosis. We herein describe the case of a patient with MGRS and the diagnostic entity involved. She responded well to the treatment as co-managed by a multidisciplinary team of nephrologists, hematologists, and renal pathologists.