# Complexities of Severe Leptospirosis: A Case With Acute Hypoxic Respiratory Failure, Acute Kidney Injury, and Hyponatremia

**Authors:** Hamza Maqbool, Waqas Memon

PMC · DOI: 10.7759/cureus.66027 · Cureus · 2024-08-02

## TL;DR

This case report details a man with severe leptospirosis who developed serious complications like respiratory failure and kidney injury.

## Contribution

The case highlights the complexities and challenges in diagnosing and managing severe leptospirosis.

## Key findings

- The patient presented with acute hypoxic respiratory failure and acute kidney injury due to rhabdomyolysis.
- Severe hyponatremia complicated the clinical course of the disease.
- The case emphasizes the need for interdisciplinary collaboration in managing such complex cases.

## Abstract

Leptospirosis, an acute zoonotic infection caused by spirochetes of the genus Leptospira, poses significant health risks worldwide. Transmission occurs through contact with infected animals' urine, blood, or tissue. This case report examines a 44-year-old man with severe leptospirosis, presenting as Weil's disease, characterized by acute hypoxic respiratory failure and acute kidney injury (AKI) secondary to rhabdomyolysis, complicated by severe hyponatremia. The case underscores the diagnostic and management challenges associated with leptospirosis, highlighting the importance of interdisciplinary collaboration and comprehensive diagnostic evaluation.

## Linked entities

- **Diseases:** leptospirosis (MONDO:0005825), Weil's disease (MONDO:0043004), acute kidney injury (MONDO:0002492), rhabdomyolysis (MONDO:0005290)

## Full-text entities

- **Diseases:** AKI (MESH:D058186), Weil's disease (MESH:D014895), Hyponatremia (MESH:D007010), Leptospirosis (MESH:D007922), rhabdomyolysis (MESH:D012206), Hypoxic Respiratory Failure (MESH:D012131)
- **Species:** Leptospira (genus) [taxon 171]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11366304/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11366304/full.md

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Source: https://tomesphere.com/paper/PMC11366304