# Calcinosis Cutis Inducing "Syringomatoid" Eccrine Hyperplasia: An Extremely Rare Example

**Authors:** Umar A Hussain, Audrey E Ahuero, Jamie A Tschen

PMC · DOI: 10.7759/cureus.66016 · Cureus · 2024-08-02

## TL;DR

This paper reports a rare case where a skin condition called syringomatoid hyperplasia occurred alongside calcinosis cutis in a 54-year-old man.

## Contribution

The novelty lies in describing the first documented case of syringomatoid hyperplasia associated with calcinosis cutis.

## Key findings

- Syringomatoid hyperplasia was observed in a patient with calcinosis cutis.
- This case suggests a possible link between calcinosis cutis and syringomatoid hyperplasia.
- The case highlights the morphological overlap between syringomas and syringomatoid hyperplasia.

## Abstract

Reactive “syringomatoid” eccrine proliferations are a well-established phenomenon, which can show similar but less extensive histological features of a syringoma. The cut-off between syringomatoid hyperplasia and syringomas is subjective and given the considerable morphological overlap, it is possible they represent two points on the same spectrum. Syringomatoid hyperplasia has been associated with several conditions including neoplasms and inflammatory dermatoses. Herein, we describe an extremely rare case of syringomatoid hyperplasia occurring with calcinosis cutis in a 54-year-old Caucasian male. To the best of the authors’ knowledge, this is the first such case described in the literature.

## Full-text entities

- **Diseases:** Eccrine Hyperplasia (MESH:D006965), neoplasms (MESH:D009369), Calcinosis Cutis (MESH:D000092182), inflammatory dermatoses (MESH:D012871), syringoma (MESH:D018252)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11366260/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC11366260/full.md

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Source: https://tomesphere.com/paper/PMC11366260