# Outcome of Primary Hyperparathyroidism: Retrospective Tertiary Center Experience From Basrah, Iraq

## TL;DR

This study examines primary hyperparathyroidism patients in Basrah, Iraq, finding it's more common in women and often symptomatic, with an 83% cure rate after surgery.

## Contribution

The study provides insights into disease characteristics and management outcomes in a tertiary center in Iraq.

## Key findings

- The mean age of presentation was 47.5 years with the highest occurrence in the sixth decade.
- 75% of patients were female with a 3:1 female-to-male ratio.
- 83% cure rate was observed in patients who underwent parathyroidectomy.

## Abstract

Background: Primary hyperparathyroidism is regarded as a common endocrine disorder that is biochemically identified and could be symptomatic or asymptomatic. A detailed history and a thorough evaluation with regular follow-ups are required until a definite diagnosis is made. The study aims to evaluate the characteristics of patients and the performance of a tertiary endocrine center in managing the disease in Basrah, Iraq.

Material and methods: A retrospective study was conducted at the Faiha Specialized Diabetes, Endocrine, and Metabolism Center in Basrah, southern Iraq, on 106 patients diagnosed with primary hyperparathyroidism between 2012 and 2023. The patients' general characteristics were assessed, and those who underwent parathyroidectomy were evaluated post-surgery, and the cure rate was determined.

Results: The mean age of presentation was 47.5 ± 14.6 years, with a median of 50 years. The highest occurrence is in the sixth decade. Females comprised 79 (75%) of the patients, and the female-to-male ratio was 3:1. Symptomatic patients were 84 (90%), 30 (70%) of the patients had nephrolithiasis, and 52 (68%) had osteoporosis. The cure rate was 15 (83%).

Conclusion: In our single-center study, the frequency of primary hyperparathyroidism has increased with time. The disease's highest occurrence was seen in the sixth decade. Females were substantially higher than males. Most patients were symptomatic. The cure rate was 83%.