Corrigendum: a novel αB-crystallin R123W variant drives hypertrophic cardiomyopathy by promoting maladaptive calcium-dependent signal transduction
Chun Chou, Gregory L. Martin, Gayani Perera, Junya Awata, Amy Larson, Robert Blanton, Michael T. Chin
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsCardiomyopathy and Myosin Studies · Cardiovascular Function and Risk Factors · Galectins and Cancer Biology
Text Correction
In the published article, there was an error. The methods section inadvertently omitted the sentence “The Cryab^R123W^ and Mybc3^Trunc^ mice were generated at the Maine Health Institute for Research Mouse Genome Modification Core Facility https://mhir.org/?page_id = 233.”
A correction has been made to Methods, Mice, Paragraph Number 1. This sentence previously stated:
“Myh6/NFAT-luc [FVB-Tg(Myh6/NFAT-luc)1 Jmol/J] reporter mice were purchased from Jackson Laboratories. The Cryab^R123W^ allele was generated via homology directed repair using the CRISPR/Cas9 system. Briefly, a guide RNA (GATCCACATCGGCT GGGATCCGG), single-stranded oligodeoxynucleotides (ssODN) donor template containing the CGG to TGG mutation, and mRNA encoding Cas9 were co-injected into the cytoplasm/pronucleus of single cell embryos.”
The corrected section appears below:
“Myh6/NFAT-luc [FVB-Tg(Myh6/NFAT-luc)1 Jmol/J] reporter mice were purchased from Jackson Laboratories. The Cryab^R123W^ and Mybc3^Trunc^ mice were generated at the Maine Health Institute for Research Mouse Genome Modification Core Facility https://mhir.org/?page_id = 233. The Cryab^R123W^ allele was generated via homology directed repair using the CRISPR/Cas9 system. Briefly, a guide RNA (GATCCACATCGGCT GGGATCCGG), single-stranded oligodeoxynucleotides (ssODN) donor template containing the CGG to TGG mutation, and mRNA encoding Cas9 were co-injected into the cytoplasm/pronucleus of single cell embryos.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.