Coexistent Eosinophilic Esophagitis and Dysplastic Barrett's Esophagus With Rapid Eosinophilic Infiltration of Neosquamous Mucosa After Radiofrequency Ablation

TL;DR

This paper reports a rare case where a patient with both Barrett's esophagus and eosinophilic esophagitis experienced rapid eosinophil infiltration after treatment.

Contribution

The study presents a unique clinical case highlighting the interaction between EoE and BE following radiofrequency ablation.

Findings

Radiofrequency ablation led to complete eradication of dysplastic Barrett's esophagus.

Rapid eosinophilic infiltration occurred in the neosquamous mucosa post-ablation.

The coexistence of EoE and BE may influence outcomes after endoscopic therapy.

Abstract

The coexistence of eosinophilic esophagitis (EoE) and Barrett's esophagus (BE) is rare despite the known association of gastroesophageal reflux disease with both conditions. Radiofrequency ablation is an effective endoscopic eradication therapy in patients with dysplastic BE. However, the efficacy and outcomes of radiofrequency ablation in patients with concomitant EoE and BE are not well known. We report a case of rapid eosinophilic infiltration of the neosquamous mucosa after the complete eradication of long-segment dysplastic BE in a patient with coexisting BE and EoE.

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